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    Michael L. Aaronson, MD
    Kidney Doctor and High Blood Pressure Specialist
    7401 O Street Lincoln, NE 68510
    Phone: 402-484-5600

    Friday, September 6, 2019

    Polycystic Kidney Disease Progression. Predicting Decline Using Total Kidney Volume.

    Thdoithcenterepresent
    patienwitpolycystikidnediseaswh
    haMayClassificatio1C
    Thipatieniahigrisfo
    progressiotkidnefailure.


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    diseas(PKD)
    genetidisordergelargean
    largekidneyovetimanma
    neetstardialysiogetransplant
    Sompatientneethestherapie
    soonerathethalaterUntinow
    nephrologisthavhadifficult
    determininwhicpatient
    arahigrisoprogression.



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    decidetexplaithproceso
    calculatintotakidnevolum
    usinthicalculatoidetaiwit
    thhopthaadoptioothi
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    volume i
    patientwitpolycystikidne
    diseastdeterminthriso
    progressio-becomemorwidesprea
    throughou
    thcountryThgoaitstratif
    risanhelpatientwitPKD 
    makdecisionregardintheicare.



    Imopinionthtoughespari
    findincentewitexpertisi
    performinaninterpretinthtest.



    FuldisclosureWperfortotakidne
    volumanhavexpertisitakin
    caropatientwit
    polycystikidnedisease.



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    Cscaothabdomewithout 
    contras(pelvinorequired)
    measurementoeackidne
    arobtaineimillimetert
    accuratelquantitatthvolumo
    thkidneysOncithscanne
    thprocedurtakeabouminutes.



    Let'ushypotheticaexamplt
    explaithusothcalculato
    usindata.



    Normakidneshowothleft
    EnlargePolycystikidneothright.

    Thnormasizekidnei
    10-1co10t11mm.


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    kidneo1co18mm.

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    thwidtwilb8mm
    anthdeptwilb10mm.

    Iwpluithnumbers, then 
    we can calculat
    thrighkidnevolumtb75m
    anthlefkidnetb75mm.

    Thtotakidnevolumi1508
    Thipatienhaverlargkidneys.


    Warabltcalculat
    thtotakidnevolumfro
    casca(Cscan).

    Iordetgethautosomadominan
    polycystikidnediseasclassification
    wneemorinformatiofroth
    patient'chartThnephrologistworkin
    closelwitthradiologistcaprovid
    thnecessardattmakthihappen.


    Let'sathpersoifeetinche
    ani4yearoldYofiltha
    informatioiangeth
    patient'classificatiowhici1C
    higrisgroup.



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    progracomeintplayan
    whimopinionpatientwit
    thidiseasshoulhavthitesdone
    yocapredicfuturGFokidne
    functiobaseothpatient'
    classificationLet'investigatthifurther:



    Let'sathipatienhaserucreatinin
    o1.1i4yearoldiwhitanfemale
    WhaithpredicteGF
    gointbiyears?


    Predicthpatient'futurGF(kidnestage
    iyohavaccestthMayCalculator



    Thanswei42Sthi


    Patienwitchronikidnediseas
    stagwillos1mpemipe
    metersquareoGFiyears
    Yocapredic1o1
    yearouiyowish.


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    feltbpossiblcandidatefo
    medicatiotherapathitim
    becaustheirisoprogressio
    issevere
    Homuccamedicatiohelp? 
    Somstudiehavshowtha
    medicatiocaextenthtimunti
    yoneetstardialysiswhiciCK
    frositninyearithGFiles
    tha6(soupatienabove)aneve
    longeamonthoswhstar
    therapearlier.

    Iyowantlearmoraboutota
    kidnevolumipolycystikidne
    disease, please asyoudoctot
    refetspecialist.

    Importanpointaothitim

    thevaluatiothawdheri
    LincolnNebraskdoeno
    loofolivecysts
    syomaneeaabdominaultrasoun
    or ct with contrast
    iaddition, ithericoncern.



    Also, our expert radiologists that we work with may see something suspicious when performing the total kidney volume test. In other words, patients with polycystic kidney disease might have a mass that might be malignant. The patient may need a CT with contrast to further delineate whether he or she has kidney cancer. If the concern arises, shared decision-making will occur, and we will treat you accordingly.

    Think about the following: if you are at high risk of progression of kidney disease and decline of renal function, you might want to think about using medication to prevent progression. Consider getting listed for transplant sooner. You might want to talk with our CKD educator sooner. And you need to start thinking about which modality of kidney replacement therapy you might want to start, such as at home peritoneal dialysis (through the belly), home hemodialysis, or in center (in a clinic) dialysis.

    All that said, we have expertise in total kidney volume and taking care of patients with polycystic kidney disease. If you would like to make an appointment with us in Lincoln, Nebraska and get evaluated, please feel free to do so.