Salt restriction of 1.5 grams per day can lower the blood pressure on average 7 mm of Hg over 3 mm Hg. This is similar to using a blood pressure medication.
If a patient has an elevated uric acid, consider using an angiotensin receptor blocker. Losartan not only lowers blood pressure but it also has a uricosuric effect. HCTZ, on the other hand, will increase the uric acid level.
When beta blockers are compared with angiotensin receptor blockers, for initial therapy, beta blockers are noted to have higher cardiovascular-related events and mortality compared with angiotensin receptor blockers.